(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

Base Information

Chemical Name:(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester
CAS No.:1029800-33-6
Molecular Formula:C₂₄H₂₈N₂O₅
Molecular Weight:424.497
Hs Code.:

Synonyms:(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

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Technology Process of (2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

There total 1 articles about (2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 1029800-32-5
(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-2-carboxylic acid

: 1029800-33-6
(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 1.5h;

Reference yield:

: 1029799-79-8
1-[4-(2-Amino-thiazol-4-yl)-phenyl]-ethanone

: 1029800-33-6
(2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester

: 1029798-81-9
(2S,5R)-2-[4-(4-cyclopropylcarbamoyl-phenyl)-thiazol-2-ylcarbamoyl]-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-l-carboxylic acid benzyl ester

Guidance literature:: (2S,5R)-5-(4-morpholin-4-ylmethyl-phenyl)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

1-[4-(2-Amino-thiazol-4-yl)-phenyl]-ethanone; In N,N-dimethyl-formamide; at 45 ℃;