Technology Process of 1-bromo-6-<(tert-butyldiphenylsilyl)oxy>-2,4,8-tetradecatriene
There total 9 articles about 1-bromo-6-<(tert-butyldiphenylsilyl)oxy>-2,4,8-tetradecatriene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; 1,2-bis-(diphenylphosphino)ethane;
In
dichloromethane;
for 0.5h;
Ambient temperature;
DOI:10.1021/jo00356a004
- Guidance literature:
-
Multi-step reaction with 9 steps
1: oxalyl chloride, DMF / benzene / Ambient temperature
2: benzene; diethyl ether / -10 - -5 °C
3: Rh(OAc)2 / 1 h / Ambient temperature
4: CeCl3*5H2O, NaBH4 / propan-2-ol; H2O
5: pyridine / 0 °C
6: imidazole / dimethylformamide / Ambient temperature
7: 98 percent / H2, pyridine / Lindlar catalyst / hexane / 10 h / 760 Torr
8: 46 percent / 80percent AcOH / 48 h / Ambient temperature
9: 96 percent / CBr4, bis(1,2-diphenylphosphino)ethane (DIPHOS) / CH2Cl2 / 0.5 h / Ambient temperature
With
rhodium(II) acetate; pyridine; 1H-imidazole; sodium tetrahydroborate; cerium(III) chloride; oxalyl dichloride; carbon tetrabromide; hydrogen; acetic acid; N,N-dimethyl-formamide; 1,2-bis-(diphenylphosphino)ethane;
Lindlar's catalyst;
In
diethyl ether; hexane; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol; benzene;
DOI:10.1021/jo00356a004
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Rh(OAc)2 / 1 h / Ambient temperature
2: CeCl3*5H2O, NaBH4 / propan-2-ol; H2O
3: pyridine / 0 °C
4: imidazole / dimethylformamide / Ambient temperature
5: 98 percent / H2, pyridine / Lindlar catalyst / hexane / 10 h / 760 Torr
6: 46 percent / 80percent AcOH / 48 h / Ambient temperature
7: 96 percent / CBr4, bis(1,2-diphenylphosphino)ethane (DIPHOS) / CH2Cl2 / 0.5 h / Ambient temperature
With
rhodium(II) acetate; pyridine; 1H-imidazole; sodium tetrahydroborate; cerium(III) chloride; carbon tetrabromide; hydrogen; acetic acid; 1,2-bis-(diphenylphosphino)ethane;
Lindlar's catalyst;
In
hexane; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jo00356a004