Technology Process of PropanaMide, N-(4-oxocyclohexyl)-
There total 2 articles about PropanaMide, N-(4-oxocyclohexyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-propionamidocyclohexanol;
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide;
In
dichloromethane;
at 0 ℃;
for 0.25h;
Green chemistry;
With
trichloroisocyanuric acid;
In
dichloromethane;
for 6h;
Temperature;
Green chemistry;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere; Reflux; Green chemistry
2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide / dichloromethane / 0.25 h / 0 °C / Green chemistry
2.2: 6 h / Green chemistry
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; triethylamine; sodium bromide;
In
dichloromethane;
- Guidance literature:
-
4-propanoamidocyclohexanone;
With
hydrogen bromide;
In
ethyl acetate;
at 20 ℃;
for 0.25h;
Green chemistry;
With
dihydrogen peroxide;
In
ethyl acetate;
at 60 ℃;
for 5h;
Green chemistry;
thiourea;
In
ethyl acetate;
for 4h;
Reflux;
Green chemistry;
