3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid

Base Information

Chemical Name:3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid
CAS No.:773872-85-8
Molecular Formula:C₁₄H₁₂O₃
Molecular Weight:228.247
Hs Code.:2918199090
DSSTox Substance ID:DTXSID10572384
Wikidata:Q82460720
Mol file:773872-85-8.mol

Synonyms:773872-85-8;3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid;4-(3-HYDROXYMETHYLPHENYL)BENZOIC ACID;4-[3-(hydroxymethyl)phenyl]benzoic acid;3'-(Hydroxymethyl)[1,1'-biphenyl]-4-carboxylic acid;3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylicacid;SCHEMBL4140814;DTXSID10572384;YFB87285;MFCD06203071;AKOS004118897;AS-3216;CS-0207428

Suppliers and Price of 3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-Hydroxymethylphenyl)benzoicacid
1g
$ 200.00

Crysdot
3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylicacid 95+%
5g
$ 339.00

American Custom Chemicals Corporation
3'-(HYDROXYMETHYL)-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID 95.00%
5MG
$ 497.32

Alichem
3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylicacid
5g
$ 400.00

AK Scientific
3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylicacid
5g
$ 531.00

AK Scientific
3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylicacid
1g
$ 120.00

Total 5 raw suppliers

Chemical Property of 3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid

Chemical Property:

PSA：57.53000
LogP:2.54410
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:228.078644241
Heavy Atom Count:17
Complexity:256

Purity/Quality:

99% ^*data from raw suppliers

4-(3-Hydroxymethylphenyl)benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C2=CC=C(C=C2)C(=O)O)CO

Technology Process of 3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid

There total 2 articles about 3'-(Hydroxymethyl)-[1,1'-biphenyl]-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15852-73-0
(3-Bromophenyl)methanol

: 14047-29-1
4-carboxyphenylboronic acid

: 773872-85-8
3'-hydroxymethyl-biphenyl-4-carboxylic acid

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 1,4-dioxane; for 1h; Heating;
DOI:10.1016/j.bmcl.2003.11.079

Reference yield:

: 15852-73-0
(3-Bromophenyl)methanol

: 99768-12-4
4-methoxycarbonylphenylboronic acid

: 773872-85-8
3'-hydroxymethyl-biphenyl-4-carboxylic acid

Guidance literature:: With caesium carbonate; In 1,4-dioxane; water;
DOI:10.1016/j.bmcl.2010.09.033

Reference yield:

: 773872-85-8
3'-hydroxymethyl-biphenyl-4-carboxylic acid

: 3'-chloromethyl-biphenyl-4-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 1 h / Heating

2: tetrahydrofuran / 12 h / 20 °C

With thionyl chloride; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2003.11.079