3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Base Information

Chemical Name:3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester
CAS No.:807619-66-5
Molecular Formula:C₃₁H₂₂Cl₅NO₅
Molecular Weight:665.784
Hs Code.:

Synonyms:3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Suppliers and Price of 3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

There total 5 articles about 3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-86-5,67471-28-7
Pentachlorophenol

: 925671-17-6
3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid

: 807619-66-5
3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Guidance literature:: With dacarbazine;
DOI:10.1021/ja0453329

Reference yield:

: 19694-02-1
Pyrene-1-carboxylic acid

: 807619-66-5
3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: oxalyl chloride / tetrahydrofuran / Heating

2: Et₃N / CH₂Cl₂ / 0.5 h / pH 8 - 8.5

3: 1.1 g / p-toluenesulfonic acid / CH₂Cl₂ / 2 h / 20 °C

4: aq. NaOH / methanol

5: N,N'-diisopropyl-carbodiimide / DMAP / tetrahydrofuran / 20 °C

With sodium hydroxide; oxalyl dichloride; triethylamine; diisopropyl-carbodiimide; dmap; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja065317z

Reference yield:

: 16331-58-1
pyren-1-ylcarbonyl chloride

: 807619-66-5
3-[(pyrene-1-carbonyl)-(tetrahydro-pyran-2-yloxy)-amino]-propionic acid pentachlorophenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂ / 0.5 h / pH 8 - 8.5

2: 1.1 g / p-toluenesulfonic acid / CH₂Cl₂ / 2 h / 20 °C

3: aq. NaOH / methanol

4: N,N'-diisopropyl-carbodiimide / DMAP / tetrahydrofuran / 20 °C

With sodium hydroxide; triethylamine; diisopropyl-carbodiimide; dmap; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja065317z