1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene

Base Information

• Chemical Name: 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene
• CAS No.: 136089-03-7
• Molecular Formula: C₃₇H₄₀O₅
• Molecular Weight: 565.714
• Mol file: 136089-03-7.mol

Synonyms:1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene

Chemical Property of 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene

There total 8 articles about 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuteriopropane-2,3-(2R)-diol 2,3-thionocarbonate (136089-06-0) → 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene (136089-03-7)

Guidance literature:

With phosphorous acid trimethyl ester; at 100 ℃; for 24h;

DOI:10.1021/jo00022a038

Reference yield:

(1R,2R)-1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1-deuteriopropane-2,3-diol (136089-04-8) → 1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuterio-2-propene (136089-03-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / benzene / 12 h / 70 °C

2: 63 percent / trimethyl phosphite / 24 h / 100 °C

With phosphorous acid trimethyl ester; In benzene;

DOI:10.1021/jo00022a038

Reference yield:

C38H39(2)HO7S (136089-06-0) → C37H39(2)HO5 (136089-03-7)

Guidance literature:

With phosphorous acid trimethyl ester; at 100 ℃; for 24h;

DOI:10.1021/jo00022a039

upstream raw materials:

1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1(R)-deuteriopropane-2,3-(2R)-diol 2,3-thionocarbonate

2,6-Anhydro-3,4,5,7-tetra-O-benzyl-aldehydo-D-glycero-D-ido-heptopyranose

2,6-anhydro-1,3,4,5-tetra-O-benzyl-D-glycero-L-gulo-heptitol

1-(2,3,4,6-O-tetrabenzyl-α-D-glucopyranosyl)-1-propen-3-ol

Downstream raw materials:

C₃₇H₄₁⁽²⁾HO₆

C₃₇H₄₁⁽²⁾HO₆