{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

Base Information

Chemical Name:{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine
CAS No.:1171042-68-4
Molecular Formula:C₃₅H₄₂N₆
Molecular Weight:546.759
Hs Code.:

Synonyms:{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

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Chemical Property of {5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

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Technology Process of {5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

There total 4 articles about {5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1171045-55-8
3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl boronic acid

: 1171043-89-2
(5-bromo-[2,2';4',3]terpyridin-6'-yl)-cyclopentyl-amine

: 1171042-68-4
{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

Guidance literature:: With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,2-dimethoxyethane; at 90 ℃; Microwave radiation;

Reference yield:

: 1122-62-9
2-acetylpyridine

: 1171042-68-4
{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 °C / Inert atmosphere of argon

2: ethanol / 120 °C / Microwave radiation

3: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,2-dimethoxyethane / 90 °C / Microwave radiation

With sodium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol;

Reference yield:

: 113118-81-3
5-bromopyridine-3-carbaldehyde

: 1171042-68-4
{5-[3-(4-tert-butyl-piperazin-1-ylmethyl)-phenyl]-[2,2';4',3]terpyridin-6'-yl}-cyclopentyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 °C / Inert atmosphere of argon

2: ethanol / 120 °C / Microwave radiation

3: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,2-dimethoxyethane / 90 °C / Microwave radiation

With sodium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol;