C₂₄H₁₆Br₂S

Base Information

• Chemical Name: C₂₄H₁₆Br₂S
• CAS No.: 536725-06-1
• Molecular Formula: C₂₄H₁₆Br₂S
• Molecular Weight: 496.265
• Mol file: 536725-06-1.mol

Synonyms:C₂₄H₁₆Br₂S

Chemical Property of C₂₄H₁₆Br₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₁₆Br₂S

There total 6 articles about C₂₄H₁₆Br₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.2%

3-[3-(3-{3-[3-(3-hydroxy-prop-1-ynyl)-phenyl]-prop-2-ynylsulfanyl}-prop-1-ynyl)-phenyl]-prop-2-yn-1-ol (536725-04-9) → C24H16Br2S (536725-06-1)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane;

DOI:10.1016/S0040-4039(03)00148-5

Reference yield:

dipropargyl sulfide (13702-09-5) → C24H16Br2S (536725-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 99.5 percent / CuI; Et₃N / Pd(PPh₃)2Cl₂

2: 95.2 percent / CBr₄; PPh₃ / CH₂Cl₂

With copper(l) iodide; carbon tetrabromide; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In dichloromethane; 1: Sonogashira coupling;

DOI:10.1016/S0040-4039(03)00148-5

Reference yield:

3-Iodoaniline (626-01-7) → C24H16Br2S (536725-06-1)

Guidance literature:

Multi-step reaction with 5 steps

1: HCl; NaNO₂; K₂CO₃ / H₂O; acetonitrile

2: 100 percent / CuI; Et₃N / Pd(PPh₃)2Cl₂

3: 94.4 percent / iodine; MeI

4: 99.5 percent / CuI; Et₃N / Pd(PPh₃)2Cl₂

5: 95.2 percent / CBr₄; PPh₃ / CH₂Cl₂

With hydrogenchloride; copper(l) iodide; carbon tetrabromide; iodine; potassium carbonate; triethylamine; triphenylphosphine; sodium nitrite; methyl iodide; bis-triphenylphosphine-palladium(II) chloride; In dichloromethane; water; acetonitrile; 2: Sonogashira coupling / 4: Sonogashira coupling;

DOI:10.1016/S0040-4039(03)00148-5

upstream raw materials:

3-[3-(3-{3-[3-(3-hydroxy-prop-1-ynyl)-phenyl]-prop-2-ynylsulfanyl}-prop-1-ynyl)-phenyl]-prop-2-yn-1-ol

dipropargyl sulfide

3-Iodoaniline

3-(3-iodo-phenyl)-prop-2-yn-1-ol