C₁₆H₂₂OS

Base Information

• Chemical Name: C₁₆H₂₂OS
• CAS No.: 1373403-54-3
• Molecular Formula: C₁₆H₂₂OS
• Molecular Weight: 262.416
• Mol file: 1373403-54-3.mol

Synonyms:C₁₆H₂₂OS

Chemical Property of C₁₆H₂₂OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₂OS

There total 3 articles about C₁₆H₂₂OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(Z)-3-hexenoic acid (1775-43-5) + 4-t-butylbenzenethiol (2396-68-1) → C16H22OS (1373403-54-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 14h;

DOI:10.1002/anie.201107317

Reference yield:

3-hexyn-1-ol (1002-28-4) → C16H22OS (1373403-54-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen / ethyl acetate / 4 h

2: sodium periodate; potassium dichromate; nitric acid / water; acetonitrile / 0 - 10 °C

3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 14 h / 0 - 20 °C

With dmap; sodium periodate; potassium dichromate; hydrogen; nitric acid; dicyclohexyl-carbodiimide; In dichloromethane; water; ethyl acetate; acetonitrile;

DOI:10.1002/anie.201107317

Reference yield:

(Z)-3-Hexen-1-ol (928-96-1) → C16H22OS (1373403-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium periodate; potassium dichromate; nitric acid / water; acetonitrile / 0 - 10 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 14 h / 0 - 20 °C

With dmap; sodium periodate; potassium dichromate; nitric acid; dicyclohexyl-carbodiimide; In dichloromethane; water; acetonitrile;

DOI:10.1002/anie.201107317

upstream raw materials:

(Z)-3-Hexen-1-ol

3-hexyn-1-ol

(Z)-3-hexenoic acid

4-t-butylbenzenethiol