(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Base Information

Chemical Name:(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol
CAS No.:100045-86-1
Molecular Formula:C₂₄H₄₁BrO₅Si
Molecular Weight:517.576
Hs Code.:

Synonyms:(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Suppliers and Price of (E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

There total 5 articles about (E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35334-60-2
(E)-6-acetoxy-4-methyl-4-hexenal

: 100045-86-1
(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Guidance literature:: Multi-step reaction with 6 steps

1: 84 percent / NaBH₄ / ethanol / 0.42 h / 25 °C

2: triethylamine / 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 h / Ambient temperature

3: K₂CO₃ / methanol / 24 h / Ambient temperature

4: 1.) n-BuLi, 2.) methanesulfonyl chloride, 3.) Li₂CuCl₄ / 1.) THF/n-hexane, -78 deg C, 35 min, 2.) -78 deg C, 2 h, 3.) THF/n-hexane/diethyl ether -78 deg C to room temp. over 2.5 h then 25 deg C, 3 h

5: 73 percent / benzene / 14 h / 120 °C / in a sealed tube

6: 85 percent / Br₂, tert butylamine / toluene / 4 h / -78 - 5 °C

With sodium tetrahydroborate; n-butyllithium; dilithium tetrachlorocuprate; bromine; potassium carbonate; methanesulfonyl chloride; tert-butylamine; triethylamine; dmap; In methanol; ethanol; dichloromethane; toluene; benzene;
DOI:10.1021/ja00264a038

Reference yield:

: 100045-79-2
<(2E)-6-Hydroxy-3-methyl-2-hexenyl>acetat

: 100045-86-1
(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / 4-(dimethylamino)pyridine / CH₂Cl₂ / 20 h / Ambient temperature

2: K₂CO₃ / methanol / 24 h / Ambient temperature

3: 1.) n-BuLi, 2.) methanesulfonyl chloride, 3.) Li₂CuCl₄ / 1.) THF/n-hexane, -78 deg C, 35 min, 2.) -78 deg C, 2 h, 3.) THF/n-hexane/diethyl ether -78 deg C to room temp. over 2.5 h then 25 deg C, 3 h

4: 73 percent / benzene / 14 h / 120 °C / in a sealed tube

5: 85 percent / Br₂, tert butylamine / toluene / 4 h / -78 - 5 °C

With n-butyllithium; dilithium tetrachlorocuprate; bromine; potassium carbonate; methanesulfonyl chloride; tert-butylamine; triethylamine; dmap; In methanol; dichloromethane; toluene; benzene;
DOI:10.1021/ja00264a038

Reference yield:

: 100045-80-5
(E)-6-((tert-butyldimethylsilyl)oxy)-3-methylhex-2-en-1-yl acetate

: 100045-86-1
(E)-2-bromo-6-(6-(tert-butyldimethylsiloxy)-3-methyl-2-hexenyl)-5-methoxy-3-(methoxymethoxymethyl)-4-methylphenol

Guidance literature:: Multi-step reaction with 4 steps

1: K₂CO₃ / methanol / 24 h / Ambient temperature

2: 1.) n-BuLi, 2.) methanesulfonyl chloride, 3.) Li₂CuCl₄ / 1.) THF/n-hexane, -78 deg C, 35 min, 2.) -78 deg C, 2 h, 3.) THF/n-hexane/diethyl ether -78 deg C to room temp. over 2.5 h then 25 deg C, 3 h

3: 73 percent / benzene / 14 h / 120 °C / in a sealed tube

4: 85 percent / Br₂, tert butylamine / toluene / 4 h / -78 - 5 °C

With n-butyllithium; dilithium tetrachlorocuprate; bromine; potassium carbonate; methanesulfonyl chloride; tert-butylamine; In methanol; toluene; benzene;
DOI:10.1021/ja00264a038