(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Base Information

Chemical Name:(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate
CAS No.:126925-59-5
Molecular Formula:C₁₉H₂₅ClO₅Si
Molecular Weight:396.943
Hs Code.:

Synonyms:(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Suppliers and Price of (2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

There total 8 articles about (2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121702-70-3
tert-Butyl-dimethyl-((2R,4aR,8S,8aR)-2-phenyl-4,4a,8,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-silane

: 126925-59-5
(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) MCPBA, 2.) Ca(OH)2 / 1.) CH₂Cl₂, 0 deg C, 45 min, 2.) CH₂Cl₂, 0 deg C, 20 min

2: NBS, BaCO₃, AIBN / CCl₄ / 0.75 h / Heating

3: n-Bu₃SnH, AIBN / benzene / 1 h / Heating

4: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1.5 h, 2.) CH₂Cl₂, from -78 to 25 deg C, 1 h

With calcium hydroxide; N-Bromosuccinimide; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; barium carbonate; In tetrachloromethane; benzene;

Reference yield:

: 150650-39-8
1-O-(3-chlorobenzoyl)-3-O-<(1,1-dimethylethyl)dimethylsilyl>-4,6-O-(phenylmethylene)-α-D-altropyranose

: 126925-59-5
(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: NBS, BaCO₃, AIBN / CCl₄ / 0.75 h / Heating

2: n-Bu₃SnH, AIBN / benzene / 1 h / Heating

3: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1.5 h, 2.) CH₂Cl₂, from -78 to 25 deg C, 1 h

With N-Bromosuccinimide; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; dimethyl sulfoxide; triethylamine; barium carbonate; In tetrachloromethane; benzene;

Reference yield:

: 150673-82-8
3-Chloro-benzoic acid (2R,3S,4S,5R,6S)-5-benzoyloxy-6-bromomethyl-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-tetrahydro-pyran-2-yl ester

: 126925-59-5
(2R)-trans-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-3,6-dihydro-6-methyl-3-oxo-2H-pyran-2-yl 3-chlorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: n-Bu₃SnH, AIBN / benzene / 1 h / Heating

2: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1.5 h, 2.) CH₂Cl₂, from -78 to 25 deg C, 1 h

With oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; dimethyl sulfoxide; triethylamine; In benzene;