6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Base Information

Chemical Name:6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol
CAS No.:666752-68-7
Molecular Formula:C₁₆H₁₇F₂N₃O₃S
Molecular Weight:369.392
Hs Code.:

Synonyms:6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Suppliers and Price of 6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

There total 2 articles about 6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 666752-67-6
2-[[(2,3-difluorophenyl)methyl]thio]-6-[[(1R)-2-hydroxy-1-methylethyl]amino]-4-pyrimidinol

: 108-24-7
acetic anhydride

: 666752-68-7
6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Guidance literature:: With pyridine; dmap; acetic acid; for 20h;

Reference yield:

: 666752-51-8
6-{[(1R)-2-hydroxy-1-methylethyl]amino}-2-mercapto-4-pyrimidinol

: 666752-68-7
6-[[(1R)-2-(acetyloxy)-1-methylethyl]amino]-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 1 h

2: pyridine; dmap; acetic acid / 20 h

With pyridine; dmap; sodium hydroxide; acetic acid; In ethanol; water;