4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride

Base Information

• Chemical Name: 4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride
• CAS No.: 191871-34-8
• Molecular Formula: C₁₁H₁₃N₃O*ClH
• Molecular Weight: 239.705

Synonyms:4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride

Chemical Property of 4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride

Chemical Property:

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Technology Process of 4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride

There total 1 articles about 4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

methanolic hydrogen chloride + 5-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]phenyl]methyl]-3-methyl-1,2,4-oxadiazole (191871-33-7) → 4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride (191871-34-8)

Guidance literature:

Reference yield: 99.0%

4-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride (191871-34-8) + (R,S)-N5-[(1,1-dimethylethoxy)carbonyl]-N2-(diphenylacetyl)-ornithine (191870-74-3) → (R,S)-N5-[(1,1-Dimethylethoxy)carbonyl]-N2-(diphenylacetyl)-N-[[4-(3-methyl-1,2,4-oxadiazol-5-yl-methyl)phenyl]methyl]-ornithinamide (191871-35-9)

Guidance literature:

With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate;

upstream raw materials:

5-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]phenyl]methyl]-3-methyl-1,2,4-oxadiazole

Downstream raw materials:

(R,S)-N₅-[(1,1-Dimethylethoxy)carbonyl]-N₂-(diphenylacetyl)-N-[[4-(3-methyl-1,2,4-oxadiazol-5-yl-methyl)phenyl]methyl]-ornithinamide

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