N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide

Base Information

• Chemical Name: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide
• CAS No.: 245125-71-7
• Molecular Formula: C₂₆H₃₄N₂P₂
• Molecular Weight: 436.517
• Mol file: 245125-71-7.mol

Synonyms:N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide

Chemical Property of N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide

There total 3 articles about N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) → N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide (245125-71-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, hexane, -130 deg C, 20 min, 2.) THF, hexane, from -130 deg C to RT

2: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, from -78 deg C to RT

With n-butyllithium;

DOI:10.1016/S0957-4166(99)00215-3

Reference yield:

2,3-dibromobenzene (583-53-9) → N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide (245125-71-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, hexane, -130 deg C, 20 min, 2.) THF, hexane, from -130 deg C to RT

2: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, from -78 deg C to RT

With n-butyllithium;

DOI:10.1016/S0957-4166(99)00215-3

Reference yield:

bis(diethylamino)chlorophosphine (685-83-6) + (2-bromophenyl)diphenylphosphane (62336-24-7) → N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide (245125-71-7)

Guidance literature:

With n-butyllithium; Yield given; Multistep reaction; 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, from -78 deg C to RT;

DOI:10.1016/S0957-4166(99)00215-3

upstream raw materials:

bis(diethylamino)chlorophosphine

(2-bromophenyl)diphenylphosphane

chloro-diphenylphosphine

2,3-dibromobenzene

Downstream raw materials:

(R)-2-<2-(diphenylphosphino)phenyl>-1,3,2-dinaphtho1,2,f^1,2>dioxaphosphepine

<2-(diphenylphosphino)phenyl>phosphonous acid dichloride