1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

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Chemical Name:1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone
CAS No.:122268-06-8
Molecular Formula:C₂₃H₂₆N₈O₃
Molecular Weight:462.511
Hs Code.:

Synonyms:1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

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Chemical Property of 1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

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Technology Process of 1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

There total 2 articles about 1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 122290-42-0
5-<4-<(4-acetyl-3-hydroxy-2-propylphenyl)methoxy>phenyl>-2H-tetrazole-2-butanenitrile

: 122268-06-8
1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

Guidance literature:: With tributyltin azide; In 1,2-dimethoxyethane; for 96h; Heating;
DOI:10.1021/jm00113a014

Reference yield:

: 97581-69-6
1-<2-hydroxy-3-propyl-4-<<4-(1H-tetrazol-5-yl)phenoxy>methyl>phenyl>ethanone

: 122268-06-8
1-[2-Hydroxy-3-propyl-4-(4-{2-[3-(1H-tetrazol-5-yl)-propyl]-2H-tetrazol-5-yl}-phenoxymethyl)-phenyl]-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / K₂CO₃ / acetone / 20 h / Ambient temperature

2: 80 percent / tributyltin azide / 1,2-dimethoxy-ethane / 96 h / Heating

With tributyltin azide; potassium carbonate; In 1,2-dimethoxyethane; acetone;
DOI:10.1021/jm00113a014