ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Base Information

Chemical Name:ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate
CAS No.:862814-79-7
Molecular Formula:C₃₀H₃₈N₄O₉S₂
Molecular Weight:662.785
Hs Code.:

Synonyms:ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Suppliers and Price of ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

There total 4 articles about ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 380897-71-2
(3-acetoxy-2-O-benzoyl-1-propoxy)methyl bromide

: 862787-43-7
ethyl α-[6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

: 862814-79-7
ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Guidance literature:: With 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1080/15257770701296952

Reference yield:

: 5334-32-7
1H-pyrazolo[3,4-d]pyrimidin-4,6-dithione

: 862814-79-7
ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / aq. sodium hydroxide / 3 h / 20 °C

2: 75 percent / 18-crown-6; potassium tert-butoxide / tetrahydrofuran / 1 h / 20 °C

With sodium hydroxide; 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran;
DOI:10.1080/15257770701296952

Reference yield:

: 533-68-6
2-bromobutyric acid ethyl ester

: 862814-79-7
ethyl α-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-6-(1'-carboethoxypropylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]thiobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / aq. sodium hydroxide / 3 h / 20 °C

2: 75 percent / 18-crown-6; potassium tert-butoxide / tetrahydrofuran / 1 h / 20 °C

With sodium hydroxide; 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran;
DOI:10.1080/15257770701296952