C₂₀H₁₄N₂OS

Base Information

• Chemical Name: C₂₀H₁₄N₂OS
• CAS No.: 1420292-67-6
• Molecular Formula: C₂₀H₁₄N₂OS
• Molecular Weight: 330.41
• Mol file: 1420292-67-6.mol

Synonyms:C₂₀H₁₄N₂OS

Chemical Property of C₂₀H₁₄N₂OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₁₄N₂OS

There total 2 articles about C₂₀H₁₄N₂OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1-iodo-4-thioacetylbenzene (69746-43-6) + 5-ethynyl-2,2'-bipyridine (162318-34-5) → C20H14N2OS (1420292-67-6)

Guidance literature:

1-iodo-4-thioacetylbenzene; 5-ethynyl-2,2'-bipyridine; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; for 1h; Inert atmosphere;

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1039/c2cc37904j

Reference yield:

5-bromo-2,2'-bipyridyl (15862-19-8) → C20H14N2OS (1420292-67-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: potassium carbonate / methanol; dichloromethane / 1 h / 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / Inert atmosphere

3.2: 20 °C / Inert atmosphere

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; 1.1: |Sonogashira Cross-Coupling / 1.2: |Sonogashira Cross-Coupling / 3.1: |Sonogashira Cross-Coupling / 3.2: |Sonogashira Cross-Coupling;

DOI:10.1039/c2cc37904j

Reference yield:

tetrakis(dimethylsulfoxide)dichlororuthenium(II) (72904-47-3,194497-67-1,64376-67-6,61779-29-1,59091-96-2,482618-33-7,90698-13-8,89395-66-4,75766-08-4,41290-68-0) + C20H14N2OS (1420292-67-6) → C60H42N6O3RuS3(2+)*2Cl(1-) + C60H43N6O3RuS3(2+)*2Cl(1-)

Guidance literature:

In ethanol; for 48h; Inert atmosphere; Reflux;

DOI:10.1039/c2cc37904j

upstream raw materials:

1-iodo-4-thioacetylbenzene

5-ethynyl-2,2'-bipyridine

5-bromo-2,2'-bipyridyl