3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid

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Chemical Name:3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid
CAS No.:1019337-41-7
Molecular Formula:C₂₈H₂₀ClFN₄O₄S
Molecular Weight:563.009
Hs Code.:

Synonyms:3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid

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Chemical Property of 3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid

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Technology Process of 3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid

There total 1 articles about 3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

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: 1019338-19-2
methyl 3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylate

: 1019337-41-7
3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylic acid

Guidance literature:: methyl 3-[[(4-chloro-2-fluorophenyl)carbonyl](tetrahydro-3-furanyl)amino]-5-(4-pyrazolo[1,5-a]pyrimidin-2-ylphenyl)-2-thiophenecarboxylate; With sodium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 48h;

With hydrogenchloride; In tetrahydrofuran; methanol; dichloromethane; water; at 20 ℃; for 0.5h;