2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate

Base Information

• Chemical Name: 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate
• CAS No.: 1240486-88-7
• Molecular Formula: C₃₇H₄₈Cl₃NO₈
• Molecular Weight: 741.149
• Mol file: 1240486-88-7.mol

Synonyms:2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate

Chemical Property of 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate

There total 1 articles about 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C35H48O8 + trichloroacetonitrile (545-06-2) → 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate (1240486-88-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jo101231r

Reference yield: 95.0%

2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate (1240486-88-7) → allyl 3-O-p-methoxybenzyl-4-O-tert-butyldimethylsilyl-α-L-rhamnopyranoside (1240486-89-8)

Guidance literature:

With sodium methylate; In methanol; at -15 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jo101231r

Reference yield: 92.0%

allyl 2-O-2(S)-methylbutyryl-3-O-p-methoxybenzyl-α-L-rhamnopyranoside (1240486-91-2) + 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl trichloroacetimidate (1240486-88-7) → allyl 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl-(1->4)-2-O-2(S)-methylbutyryl-3-O-p-methoxybenzyl-α-L-rhamnopyranoside (1240486-97-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 - 25 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1021/jo101231r

upstream raw materials:

trichloroacetonitrile

Downstream raw materials:

allyl 3-O-p-methoxybenzyl-4-O-tert-butyldimethylsilyl-α-L-rhamnopyranoside

allyl 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl-(1->4)-2-O-2(S)-methylbutyryl-3-O-p-methoxybenzyl-α-L-rhamnopyranoside

allyl 2-O-trans-cinnamoyl-3-O-p-methoxybenzyl-4-O-n-dodecanoyl-α-L-rhamnopyranosyl-(1→4)-2-O-2(S)-methylbutyryl-3-O-(11(S)-levulinoyloxyhexadecanoyl)-α-L-rhamnopyranoside