1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride

Base Information

• Chemical Name: 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride
• CAS No.: 69716-74-1
• Molecular Formula: C₁₁H₁₅NO₂*ClH
• Molecular Weight: 229.707
• Mol file: 69716-74-1.mol

Synonyms:1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride

Chemical Property of 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride

Chemical Property:

• Melting Point: 272–273°C

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride

There total 2 articles about 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

p-hydroxyphenacyl chloride (6305-04-0) + isopropylamine (75-31-0) → 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride (69716-74-1)

Guidance literature:

p-hydroxyphenacyl chloride; isopropylamine; In methanol; at 20 ℃; for 3h;

With hydrogenchloride; In methanol; water;

Reference yield: 72.0%

2-chloro-1-(4-chloroacetoxy-phenyl)-ethanone (868746-76-3) + isopropylamine (75-31-0) → 1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride (69716-74-1)

Guidance literature:

2-chloro-1-(4-chloroacetoxy-phenyl)-ethanone; isopropylamine; In methanol; at 20 ℃; for 6h;

With hydrogenchloride; In methanol; water;

Reference yield: 91.0%

1-(4-hydroxy-phenyl)-2-isopropylamino-ethanone; hydrochloride (69716-74-1) → Paraproterenol hydrochloride (23239-36-3)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

upstream raw materials:

2-chloro-1-(4-chloroacetoxy-phenyl)-ethanone

isopropylamine

p-hydroxyphenacyl chloride

Downstream raw materials:

Paraproterenol hydrochloride