N-(2-chloro-4-nitrophenyl)-4-methylbenzamide

Base Information

Chemical Name:N-(2-chloro-4-nitrophenyl)-4-methylbenzamide
CAS No.:101078-46-0
Molecular Formula:C₁₄H₁₁ClN₂O₃
Molecular Weight:290.706
Hs Code.:
DSSTox Substance ID:DTXSID901258170

Synonyms:N-(2-chloro-4-nitrophenyl)-4-methylbenzamide;Oprea1_078856;DTXSID901258170;AKOS003855873;101078-46-0

Suppliers and Price of N-(2-chloro-4-nitrophenyl)-4-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-(2-chloro-4-nitrophenyl)-4-methylbenzamide

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:290.0458199
Heavy Atom Count:20
Complexity:364

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])Cl

Technology Process of N-(2-chloro-4-nitrophenyl)-4-methylbenzamide

There total 2 articles about N-(2-chloro-4-nitrophenyl)-4-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 874-60-2
4-methyl-benzoyl chloride

: 121-87-9
2-Chloro-4-nitroaniline

: 101078-46-0
4-methyl-2'-chloro-4'-nitrobenzanilide

Guidance literature:: With pyridine; at 100 ℃; for 0.5h;
DOI:10.1021/jm00155a037

Reference yield:

: 99-94-5
p-Toluic acid

: 101078-46-0
4-methyl-2'-chloro-4'-nitrobenzanilide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂, DMF / 1.5 h / Heating

2: 79 percent / pyridine / 0.5 h / 100 °C

With pyridine; thionyl chloride; N,N-dimethyl-formamide;
DOI:10.1021/jm00155a037