5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

Base Information

• Chemical Name: 5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide
• CAS No.: 330861-70-6
• Molecular Formula: C₁₉H₁₈BrF₃N₂O₃
• Molecular Weight: 459.263

Synonyms:5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

Chemical Property of 5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

Chemical Property:

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Technology Process of 5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

There total 1 articles about 5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) + copper(II) oxide + 5-Amino-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-benzamide (311769-61-6) → 5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide (330861-70-6)

Guidance literature:

With ammonium hydroxide; hydrogen bromide; sodium nitrite; In methanol; water; acetone;

Reference yield:

5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide (330861-70-6) → 5-[2-carbamoyl-2-(methylthio)ethyl]-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

Guidance literature:

With sodium thiomethoxide; In ethanol; water;

Reference yield:

5-(2-bromo-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide (330861-70-6) + potassium thioacetate (10387-40-3) → 5-(2-acetylthio-2-carbamoylethyl)-2-methoxy-N-(4-trifluoromethylbenzyl)benzamide

Guidance literature:

In tetrahydrofuran; ethyl acetate;

upstream raw materials:

2-propenamide

5-Amino-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-benzamide

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