Technology Process of (2R,3S)-3-phenyloxiranecarboxylic acid
There total 12 articles about (2R,3S)-3-phenyloxiranecarboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium periodate; sodium hydrogencarbonate;
ruthenium trichloride;
In
tetrachloromethane; water; acetonitrile;
for 43h;
DOI:10.1016/S0040-4039(00)01949-3
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / Ti(i-PrO)4; molecular sieves; t-BuO2H / (+)-diethyl tartrate / CH2Cl2 / 0.75 h / -20 - 0 °C
2: RuCl3*H2O; aq. NaIO4; NaHCO3 / acetonitrile; CCl4 / 1 h
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; ruthenium trichloride; sodium periodate; molecular sieve; sodium hydrogencarbonate;
(+)-Weinsaeure-diethylester;
In
tetrachloromethane; dichloromethane; acetonitrile;
1: Sharpless epoxidation;
DOI:10.1021/jo020352j
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / (+)-DET; Ti(OiPr)4 / CH2Cl2 / -20 °C
2: 65 percent / NaIO4; NaHCO3 / RuCl3*H2O / acetonitrile; CCl4; H2O / 43 h
With
titanium(IV) isopropylate; sodium periodate; diethyl (2R,3R)-tartrate; sodium hydrogencarbonate;
ruthenium trichloride;
In
tetrachloromethane; dichloromethane; water; acetonitrile;
1: Sharpless epoxidation;
DOI:10.1016/S0040-4039(00)01949-3
