methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Base Information

Chemical Name:methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate
CAS No.:1133001-16-7
Molecular Formula:C₂₆H₃₃N₃O₅S₂
Molecular Weight:531.697
Hs Code.:

Synonyms:methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Suppliers and Price of methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

There total 9 articles about methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1133001-14-5
2-(4-(4-methoxy-4-oxobutoxy)phenyl)-2-methylpropanoic acid

: 224436-97-9
2-amino-5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-thiazole

: 1133001-16-7
methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;

Reference yield:

: 76779-98-1
1-azido-3,3-dimethyl-2-butanone

: 1133001-16-7
methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol

2.1: triethylamine / dichloromethane / 1.25 h / -10 - -5 °C

3.1: trichlorophosphate / 1 h / 105 °C

4.1: ethanol; sodium tetrahydroborate / acetone / 1 h / 20 °C

4.2: 1 h / Reflux

5.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 50 °C / Inert atmosphere

With hydrogenchloride; sodium tetrahydroborate; ethanol; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trichlorophosphate; palladium 10% on activated carbon; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone;

Reference yield:

: 13547-70-1
1-chloro-3,3-dimethyl-butan-2-one

: 1133001-16-7
methyl 4-(4-(1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-ylamino)-2-methyl-1-oxopropan-2-yl)phenoxy)butanoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium azide / acetone / 25 °C

2.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol

3.1: triethylamine / dichloromethane / 1.25 h / -10 - -5 °C

4.1: trichlorophosphate / 1 h / 105 °C

5.1: ethanol; sodium tetrahydroborate / acetone / 1 h / 20 °C

5.2: 1 h / Reflux

6.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 50 °C / Inert atmosphere

With hydrogenchloride; sodium tetrahydroborate; sodium azide; ethanol; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trichlorophosphate; palladium 10% on activated carbon; In methanol; dichloromethane; N,N-dimethyl-formamide; acetone;