CyPPA

Base Information

Chemical Name:CyPPA
CAS No.:73029-73-9
Molecular Formula:C₁₆H₂₃N₅
Molecular Weight:285.392
Hs Code.:2933990090
European Community (EC) Number:635-289-8
DSSTox Substance ID:DTXSID20358676
Nikkaji Number:J2.660.959C
Wikidata:Q27076959
Pharos Ligand ID:U535PB54ACKN
ChEMBL ID:CHEMBL453730
Mol file:73029-73-9.mol

Synonyms:CyPPA;73029-73-9;N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine;cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine;CHEMBL453730;N-cyclohexyl-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine;C16H23N5;N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine;D00DIF;GTPL2323;SCHEMBL3233745;DTXSID20358676;HMS3262M15;HMS3742C19;AMY18135;EX-A5595;Tox21_500707;BDBM50275157;CyPPA, >=98% (HPLC), solid;HB1044;STK052676;AKOS015999173;CCG-222011;CS-W012225;HY-W011509;LP00707;SDCCGSBI-0633746.P001;NCGC00186022-01;NCGC00186022-05;NCGC00261392-01;MS-24068;F85618;Q27076959;2-(3,5-Dimethyl-1H-pyrazole-1-yl)-4-methyl-6-(cyclohexylamino)pyrimidine

Suppliers and Price of CyPPA

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
CyPPA
10mg
$ 438.00

TRC
CyPPA
10mg
$ 100.00

Tocris
CyPPA ≥99%(HPLC)
25
$ 389.00

Tocris
CyPPA ≥99%(HPLC)
5
$ 103.00

Sigma-Aldrich
CyPPA ≥98% (HPLC), solid
5mg
$ 124.00

Sigma-Aldrich
CyPPA ≥98% (HPLC), solid
25mg
$ 553.00

Chemenu
N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
1g
$ 1219.00

Chemenu
N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
100mg
$ 392.00

Chemenu
N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
250mg
$ 610.00

Cayman Chemical
CyPPA ≥98%
50mg
$ 509.00

Total 17 raw suppliers

Chemical Property of CyPPA

Chemical Property:

PSA：55.63000
Density:1.23
LogP:3.40510
Storage Temp.:2-8°C
Solubility.:DMSO: >10mg/mL
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:285.19534575
Heavy Atom Count:21
Complexity:331

Purity/Quality:

99%, ^*data from raw suppliers

CyPPA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)N2C(=CC(=N2)C)C)NC3CCCCC3
Uses CyPPA is a positive SK3/SK2 modulator that reduces the activity of dopaminergic neurons, inhibits dopamine release, and counteracts hyperdopaminergic behaviors induced by methyl phenidate. CyPPA has been used:to test its inhibitory functionality on melanogenesisas an activator of small conductance potassium channel-3 (SK3) in mesenteric artery segmentsin the activation of calcium-activated potassium (SK) channels in murine hippocampal neurons HT-22 cells

Technology Process of CyPPA

There total 2 articles about CyPPA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%