(S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride

Base Information

• Chemical Name: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride
• CAS No.: 126301-23-3
• Molecular Formula: C₁₀H₁₅NO₃S*ClH
• Molecular Weight: 265.761
• Mol file: 126301-23-3.mol

Synonyms:(S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride

Chemical Property of (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride

There total 3 articles about (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate (126301-19-7,134807-64-0,109687-66-3) → (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride (126301-23-3)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

Reference yield:

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester (51987-73-6) → (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride (126301-23-3)

Guidance literature:

Multi-step reaction with 3 steps

1: LiBH₄ / ethanol

2: 93 percent / triethylamine / CH₂Cl₂ / 0.5 h / 0 °C

3: 100 percent / 4 M HCl / dioxane / 1 h / Ambient temperature

With hydrogenchloride; lithium borohydride; triethylamine; In 1,4-dioxane; ethanol; dichloromethane;

Reference yield:

(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol (66605-57-0) → (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride (126301-23-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / triethylamine / CH₂Cl₂ / 0.5 h / 0 °C

2: 100 percent / 4 M HCl / dioxane / 1 h / Ambient temperature

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;

upstream raw materials:

(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester

(S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol

Downstream raw materials:

(S)-2-amino-3-phenylpropane-1-sulfonic acid