(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Base Information

Chemical Name:(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane
CAS No.:603039-46-9
Molecular Formula:C₂₃H₃₀O₃Si
Molecular Weight:382.575
Hs Code.:

Synonyms:(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Suppliers and Price of (5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

There total 7 articles about (5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 116223-21-3
(3R,4S)-4-[(t-butyldiphenylsilyl)oxy]pent-1-yn-3-ol

: 603039-46-9
(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Guidance literature:: With chloromethyl methyl ether; diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 48h;

Reference yield:

: 107-30-2
chloromethyl methyl ether

: 116223-21-3
(3R,4S)-4-[(t-butyldiphenylsilyl)oxy]pent-1-yn-3-ol

: 603039-46-9
(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.24820/ark.5550190.p010.939

Reference yield:

: 189630-90-8
(4S,2E)-4-[(tert-butyldiphenylsilyl)oxy]pent-2-en-1-ol

: 603039-46-9
(5R,6S)-5-Ethynyl-6,9,9-trimethyl-8,8-diphenyl-2,4,7-trioxa-8-siladecane

Guidance literature:: Multi-step reaction with 4 steps

1: titanium(IV) isopropylate; tert.-butylhydroperoxide / dichloromethane / 12 h / -20 °C / Molecular sieve

2: triphenylphosphine; tetrachloromethane / 5 h / Reflux

3: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C / Reflux; Inert atmosphere

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; tetrachloromethane; n-butyllithium; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; 1: |Sharpless Asymmetric Epoxidation;
DOI:10.24820/ark.5550190.p010.939