(2S)-2-(4-Nitrophenyl)oxirane

Base Information

Chemical Name:(2S)-2-(4-Nitrophenyl)oxirane
CAS No.:78038-43-4
Molecular Formula:C₈H₇NO₃
Molecular Weight:165.148
Hs Code.:
European Community (EC) Number:625-073-1,625-691-1
Nikkaji Number:J415.676E
Wikidata:Q27095519
Metabolomics Workbench ID:149213
Mol file:78038-43-4.mol

Synonyms:(S)-4-Nitrostyrene oxide;(2S)-2-(4-NITROPHENYL)OXIRANE;(S)-PARA-NITROSTYRENE OXIDE;(S)-p-Nitrostyrene oxide;Oxirane, (4-nitrophenyl)-, (2S)-;(R)-(4-Nitrophenyl)oxirane;78038-43-4;(S)-2-(4-Nitrophenyl)oxirane;(2R)-2-(4-NITROPHENYL)OXIRANE;78038-42-3;(S)-para-nitro styrene oxide;SCHEMBL1583098;AKOS017390829;DB04782;EN300-1857252;Q27095519

Suppliers and Price of (2S)-2-(4-Nitrophenyl)oxirane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(4-Nitrophenyl)oxirane
500mg
$ 1320.00

Medical Isotopes, Inc.
(R)-(4-Nitrophenyl)oxirane
50 mg
$ 650.00

Crysdot
(R)-2-(4-Nitrophenyl)oxirane 95+%
1g
$ 574.00

Chemenu
(R)-2-(4-Nitrophenyl)oxirane 95%
1g
$ 542.00

American Custom Chemicals Corporation
(R)-2-(4-NITROPHENYL)OXIRANE 95.00%
1G
$ 711.89

Alichem
(R)-2-(4-Nitrophenyl)oxirane
1g
$ 574.20

Total 9 raw suppliers

Chemical Property of (2S)-2-(4-Nitrophenyl)oxirane

Chemical Property:

Vapor Pressure:0.00175mmHg at 25°C
Refractive Index:1.611
Boiling Point:302.7°C at 760 mmHg
Flash Point:158°C
PSA：58.35000
Density:1.372g/cm³
LogP:2.18930
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:165.042593085
Heavy Atom Count:12
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

(R)-(4-Nitrophenyl)oxirane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(O1)C2=CC=C(C=C2)[N+](=O)[O-]
Isomeric SMILES:C1[C@@H](O1)C2=CC=C(C=C2)[N+](=O)[O-]
Uses (R)-(4-Nitrophenyl)oxirane is used as a reagent in the enantioconvergent synthesis of the β-blocker (R)-Nifenalol which is based on a combined chemoenzymic approach.

Technology Process of (2S)-2-(4-Nitrophenyl)oxirane

There total 46 articles about (2S)-2-(4-Nitrophenyl)oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 357952-87-5
(S)-(+)-1-(4-Nitrophenyl)-2-(p-tolylsulfonyloxy)ethanol

: 6388-74-5,53631-32-6,78038-43-4,78038-42-3,38201-14-8,71884-55-4
(S)-2-(4-nitrophenyl)oxirane

Guidance literature:: With sodium hydroxide; In diethyl ether; at 20 ℃; for 3h;
DOI:10.1039/b010155i

Reference yield: 85.0%

: 216160-44-0
(S)-2-chloro-1-(4-nitrophenyl)ethanol

: 6388-74-5,53631-32-6,78038-43-4,78038-42-3,38201-14-8,71884-55-4
(S)-2-(4-nitrophenyl)oxirane

Guidance literature:: With sodium hydroxide; In methanol; water; for 3h; Ambient temperature;
DOI:10.1016/S0040-4020(98)00796-0

Reference yield: 41.0%

: 6388-74-5,38201-14-8,71884-55-4
p-Nitrophenyloxirane

: 6388-74-5,53631-32-6,78038-43-4,78038-42-3,38201-14-8,71884-55-4
(S)-2-(4-nitrophenyl)oxirane

: 77977-74-3,88057-19-6,141725-14-6,77977-75-4
(S)-(+)-1-(4-nitrophenyl)-1,2-ethanediol

: 77977-74-3
(R)-(-)-1-(4-nitrophenyl)-1,2-ethanediol

Guidance literature:: With Yarrowia lipolytica epoxide hydrolase (Oxy-4); water; optical yield given as %ee; Enzymatic reaction;
DOI:10.1016/j.tetlet.2008.08.097