L-Tyrosine-D2

Base Information

• Chemical Name: L-Tyrosine-D2
• CAS No.: 72963-27-0
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 183.175
• European Community (EC) Number: 694-717-1
• DSSTox Substance ID: DTXSID30583957
• Wikidata: Q82475575
• Mol file: 72963-27-0.mol

Synonyms:L-Tyrosine-D2;72963-27-0;(2S)-2-amino-3,3-dideuterio-3-(4-hydroxyphenyl)propanoic acid;L-TYROSINE (3,3-D2);l-tyrosine-beta,beta-d2;DTXSID30583957;HY-N0473S8;L-(beta,beta-~2~H_2_)Tyrosine;MS-22977;CS-0376457;D99090;L-Tyrosine-3,3-d2, 98 atom % D, 99% (CP);(2S)-2-amino-3-(4-hydroxyphenyl)(3,3-?H?)propanoic acid

Chemical Property of L-Tyrosine-D2

Chemical Property:

• Melting Point: >300 °C (dec.)(lit.)
• PSA: 83.55000
• LogP: 1.04690
• XLogP3: -2.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 183.086446705
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

98%min ^*data from raw suppliers

L-Tyrosine-d2 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(C(=O)O)N)O
• Isomeric SMILES: [2H]C([2H])(C1=CC=C(C=C1)O)[C@@H](C(=O)O)N
• Uses: L-Tyrosine-d2 is deuterium labelled L-Tyrosine (H899975), which is one of the 22 proteinogenic amino acids that are used by cells to synthesize proteins. L-Tyrosine is biologically converted from L-phenylalanine and is in turn is converted to L-DOPA and further converted into the neurotransmitters: dopamine, norepinephrine, and epinephrine.

Technology Process of L-Tyrosine-D2

There total 3 articles about L-Tyrosine-D2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ DL-<3-D2>-Tyrosin (35693-18-6,72963-27-0)

Guidance literature:

aus Propionester 6;

Reference yield:

→ DL-<α,β,β-d3>-Tyrosin (63570-48-9,72963-27-0)

Guidance literature:

4b, 1.DBr 2. Spaltung in die Enantiomeren 6a und 6b ueber N-Trifluoracetylverb. 3. enzym. Hydrolyse;

DOI:10.1021/ja00447a046

Reference yield:

→ 2-amino-2,3,3-trideuterio-3-(2,6-dideuterio-4-hydroxy-phenyl)-propionic acid (39748-78-2,72963-27-0,71939-39-4)

Guidance literature:

/BRN= 878303/, 6M-DCl;

Downstream raw materials:

C₁₆H₁₉⁽²⁾H₂NO₇

[5,5-⁽²⁾H₂]phomamide