4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Base Information

Chemical Name:4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine
CAS No.:1392760-28-9
Molecular Formula:C₁₆H₁₉Cl₂N₃OS
Molecular Weight:372.318
Hs Code.:

Synonyms:4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Suppliers and Price of 4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

There total 3 articles about 4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 3240-94-6
N-(2-chlorethyl)morpholine

: 1392755-40-6
1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazole-3-thiol

: 1392760-28-9
4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Guidance literature:: With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 95 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jm3007323

Reference yield:

: 13123-99-4
2-acetyl-1-(3,4-dichlorophenyl)hydrazine

: 1392760-28-9
4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Guidance literature:: Multi-step reaction with 3 steps

1.1: phosphorus trichloride / 50 °C

2.1: tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / Reflux; Inert atmosphere

2.2: Reflux

3.1: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 18 h / 95 °C / Inert atmosphere

With tetraphosphorus decasulfide; potassium carbonate; sodium iodide; phosphorus trichloride; In 5,5-dimethyl-1,3-cyclohexadiene; N,N-dimethyl-formamide;
DOI:10.1021/jm3007323

Reference yield:

: 14575-30-5
1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ol

: 1392760-28-9
4-{2-[1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazol-3-ylthio]ethyl}morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / Reflux; Inert atmosphere

2: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 18 h / 95 °C / Inert atmosphere

With tetraphosphorus decasulfide; potassium carbonate; sodium iodide; In 5,5-dimethyl-1,3-cyclohexadiene; N,N-dimethyl-formamide;
DOI:10.1021/jm3007323