(2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

Base Information

Chemical Name:(2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester
CAS No.:1088482-05-6
Molecular Formula:C₂₉H₃₈N₂O₂
Molecular Weight:446.633
Hs Code.:

Synonyms:(2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

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Technology Process of (2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

There total 1 articles about (2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1088481-91-7
N-(3'-cyanobenzyl)-N,N-dimethyl-N-{(1S)-1-[(-)-8-phenylmenthyloxycarbonylethyl]}ammonium bromide

: 1088482-05-6
(2S)-2-(4'-cyano-2'-methylphenyl)-2-dimethylaminopropionic acid (-)-8-phenylmenthol ester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -60 ℃; for 4h; diastereoselective reaction; Inert atmosphere;
DOI:10.1039/b811162f