2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate

Base Information

• Chemical Name: 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate
• CAS No.: 1355078-56-6
• Molecular Formula: C₁₉H₂₉NO₄
• Molecular Weight: 335.444
• Mol file: 1355078-56-6.mol

Synonyms:2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate

Chemical Property of 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate

Chemical Property:

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Technology Process of 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate

There total 1 articles about 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

iodomethyl pivaloate (53064-79-2) + 4-methylbenzaldehyde N-(tert-butoxycarbonyl)imine (479423-39-7) → 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate (1355078-56-6)

Guidance literature:

With triethyl borane; sodium hydroxide; In hexane; dichloromethane; at -20 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jo2025042

upstream raw materials:

iodomethyl pivaloate

4-methylbenzaldehyde N-(tert-butoxycarbonyl)imine