1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline

Base Information

• Chemical Name: 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline
• CAS No.: 122456-32-0
• Molecular Formula: C₁₉H₁₈N₂O₃
• Molecular Weight: 322.364

Synonyms:1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline

Chemical Property of 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline

There total 4 articles about 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

salt water + 6-methoxy-3,5-dihydro-2H-furo[3,2-c]quinolin-4-one (88893-60-1) → 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline (122456-32-0)

Guidance literature:

In o-toluidine; diethylene glycol;

Reference yield:

methanolic ammonia + 2-(2-ethoxyethyl)-N,N'-bis(2-methoxyphenyl)malondiamide (122456-55-7) → 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline (122456-32-0)

Guidance literature:

In diphenylether; dichloromethane;

Reference yield:

2-(2-ethoxyethyl)-N,N'-bis(2-methoxyphenyl)malondiamide (122456-55-7) → 6-methoxy-3,5-dihydro-2H-furo[3,2-c]quinolin-4-one (88893-60-1) + 1-(2-methoxyphenyl)-4-oxo-6-methoxy-2,3,4,5-tetrahydropyrrolo<3,2-c>quinoline (122456-32-0)

Guidance literature:

In diphenylether; for 9h; Title compound not separated from byproducts; Heating;

DOI:10.1021/jm00088a021

upstream raw materials:

2-(2-ethoxyethyl)-N,N'-bis(2-methoxyphenyl)malondiamide

diethyl 2-ethoxyethylmalonate

6-methoxy-3,5-dihydro-2H-furo[3,2-c]quinolin-4-one

Downstream raw materials:

1-(2-methoxyphenyl)-4-amino-6-methoxy-2,3-dihydropyrrolo<3,2-c>quinoline

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