(2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Base Information

• Chemical Name: (2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid
• CAS No.: 923984-61-6
• Molecular Formula: C₁₆H₂₃NO₃
• Molecular Weight: 277.364
• Mol file: 923984-61-6.mol

Synonyms:(2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Chemical Property of (2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

There total 1 articles about (2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-5,5-dimethyl-4-oxohex-2-enoic acid (20972-41-2) + (S)-1-phenyl-ethylamine (2627-86-3) → (2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid (923984-61-6) + (2R)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Guidance literature:

In ethanol; at 20 ℃; for 72h;

DOI:10.1055/s-2006-950319

Reference yield: 92.0%

(2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid (923984-61-6) → (2S,4R)-4-hydroxy-5,5-dimethyl-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Guidance literature:

With sodium tetrahydroborate; manganese(ll) chloride; In methanol; at 0 - 5 ℃; for 0.5h;

DOI:10.1055/s-2006-950319

Reference yield:

(2S)-5,5-dimethyl-4-oxo-2-[(1S)-(1-phenylethyl)amino]hexanoic acid (923984-61-6) → (2S)-4-hydroxy-5,5-dimethyl-2-[(1S)-(1-phenylethyl)amino]hexanoic acid

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃;

DOI:10.1055/s-2006-950319

upstream raw materials:

(E)-5,5-dimethyl-4-oxohex-2-enoic acid

(S)-1-phenyl-ethylamine