3-(aminomethyl)-N-methylaniline

Base Information

• Chemical Name: 3-(aminomethyl)-N-methylaniline
• CAS No.: 768343-60-8
• Molecular Formula: C8H12 N2
• Molecular Weight: 136.197
• Hs Code.: 2921590090
• European Community (EC) Number: 674-291-3
• DSSTox Substance ID: DTXSID20375424
• Wikidata: Q82163956
• Mol file: 768343-60-8.mol

Synonyms:3-(aminomethyl)-N-methylaniline;768343-60-8;N-[3-(Aminomethyl)phenyl]-N-methylamine;3-Methylaminobenzylamine;3-(methylamino)benzylamine;(3-methylamino)benzylamine;MFCD04037894;n-(3-(aminomethyl)phenyl)-n-methylamine;SCHEMBL2291506;DTXSID20375424;XDEDGESLTYFNGL-UHFFFAOYSA-N;AKOS006228836;PS-5933;SB75463;n-((3-aminomethyl)phenyl)-n-methylamine;SY025093;3-(Aminomethyl)-N-methylaniline, AldrichCPR;CS-0455685;FT-0676938;EN300-1235038;A865405

Chemical Property of 3-(aminomethyl)-N-methylaniline

Chemical Property:

• Vapor Pressure: 0.0062mmHg at 25°C
• Melting Point: 143-146°
• Refractive Index: 1.603
• Boiling Point: 148-152°C
• Flash Point: 136.9°C
• PSA: 38.05000
• Density: 1.056g/cm³
• LogP: 1.96030
• Storage Temp.: 2-8°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 136.100048391
• Heavy Atom Count: 10
• Complexity: 93.3

Purity/Quality:

98%min ^*data from raw suppliers

3-(Methylamino)benzylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=CC=CC(=C1)CN

Technology Process of 3-(aminomethyl)-N-methylaniline

There total 1 articles about 3-(aminomethyl)-N-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl [3-(methylamino)benzyl]carbamate (697306-52-8) → (3-aminomethyl-phenyl)-methylamine (768343-60-8)

Guidance literature:

Acidic conditions;

Reference yield: 99.0%

di-tert-butyl dicarbonate (24424-99-5) + (3-aminomethyl-phenyl)-methylamine (768343-60-8) → tert-butyl [3-(methylamino)benzyl]carbamate (697306-52-8)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

Reference yield: 80.0%

6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinic acid (639091-33-1) + (3-aminomethyl-phenyl)-methylamine (768343-60-8) → 6-{4-[(3-fluorobenzyl)oxy]phenoxy}-N-[3-(methylamino)benzyl]nicotinamide

Guidance literature:

With water-soluble carbodiimide *HCl; benzotriazol-1-ol; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.bmc.2004.10.047

upstream raw materials:

tert-butyl [3-(methylamino)benzyl]carbamate

Downstream raw materials:

tert-butyl [3-(methylamino)benzyl]carbamate

N-[3-(methylamino)benzyl]-4-[(trifluoromethyl)thio]benzamide

Refernces