1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane

Base Information

• Chemical Name: 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane
• CAS No.: 132610-21-0
• Molecular Formula: C₁₅H₁₈OS₂
• Molecular Weight: 278.439
• Mol file: 132610-21-0.mol

Synonyms:1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane

Chemical Property of 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane

There total 3 articles about 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

trimethylsulfoxonium iodide (1774-47-6) + (Z)-1,1-Bis-methylsulfanyl-5-p-tolyl-penta-1,4-dien-3-one (89812-51-1,111222-14-1) → 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane (132610-21-0)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 50 ℃;

DOI:10.1016/S0040-4039(00)87848-X

Reference yield: 92.0%

trimethylsulfoxonium iodide (1774-47-6) + (E)-1,1-bis(methylthio)-5-(p-tolyl)penta-1,4-dien-3-one (89812-51-1) → 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane (132610-21-0)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 50 ℃; for 7h;

Reference yield:

C14H16OS2 → 1-<2-bis(methylthio)methyleneacetyl>-2-(3,4-methylenedioxyphenyl)cyclopropane (132610-21-0)

Guidance literature:

With tetrabutylammomium bromide; trimethylsulfoxonium iodide; sodium hydroxide; In dichloromethane; water; at 50 ℃;

DOI:10.1021/acs.joc.8b00775

upstream raw materials:

trimethylsulfoxonium iodide

(E)-1,1-bis(methylthio)-5-(p-tolyl)penta-1,4-dien-3-one

(Z)-1,1-Bis-methylsulfanyl-5-p-tolyl-penta-1,4-dien-3-one

Downstream raw materials:

3-(4-Methylphenyl)cyclopentanone