1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide

Base Information

• Chemical Name: 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide
• CAS No.: 109741-76-6
• Molecular Formula: Br*C₂₄H₂₆NO₄
• Molecular Weight: 472.379
• Mol file: 109741-76-6.mol

Synonyms:1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide

Chemical Property of 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide

There total 1 articles about 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-ethylpyridine (536-78-7,151103-56-9) + 2-(benzyloxy)-3,4-dimethoxyphenacyl bromide (56774-66-4) → 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide (109741-76-6)

Guidance literature:

In benzene; Ambient temperature;

DOI:10.1248/cpb.34.496

Reference yield: 94.0%

1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide (109741-76-6) → 1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium perchlorate

Guidance literature:

With sodium perchlorate; In water;

DOI:10.1248/cpb.34.496

Reference yield:

1-(2-benzyloxy-3,4-dimethoxyphenacyl)-3-ethylpyridinium bromide (109741-76-6) → (+/-)-1-(3,4-dimethoxy-2-hydroxyphenethyl)-3-ethyl-2-piperidone (109741-73-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) H₂; 2.) NaBH₄ / 1.) Adams catalyst / 1.) EtOH, 24 deg C, 2 h; 2.) RT

2: Hg(OAc)2-EDTA / aq. acetic acid / 1.5 h / Heating

3: 87 percent / H₂ / 10 percent Pd-C / ethanol; aq. HClO₄ / Ambient temperature

With sodium tetrahydroborate; Hg(OAc)2*EDTA; hydrogen; platinum(IV) oxide; palladium on activated charcoal; In perchloric acid; ethanol; acetic acid;

DOI:10.1248/cpb.34.496

upstream raw materials:

3-ethylpyridine

2-(benzyloxy)-3,4-dimethoxyphenacyl bromide

Downstream raw materials:

(+/-)-1-(2-benzyloxy-3,4-dimethoxyphenyl)-2-(3-ethylpiperidino)ethanol

(+/-)-1-(3,4-dimethoxy-2-hydroxyphenethyl)-3-ethyl-2-piperidone

(+/-)-1-<2-(2-benzyloxy-3,4-dimethyloxyphenyl)-2-hydroxyethyl>-3-ethyl-2-piperidone

(+/-)-1-<2-(2-benzyloxy-3,4-dimethyloxyphenyl)-2-hydroxyethyl>-5-ethyl-2-piperidone