(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Base Information

Chemical Name:(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal
CAS No.:243468-87-3
Molecular Formula:C₂₂H₃₈O₄Si
Molecular Weight:394.627
Hs Code.:

Synonyms:(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Suppliers and Price of (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

There total 6 articles about (3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 243468-76-0
(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexan-1-ol

: 243468-87-3
(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃; for 0.5h;
DOI:10.1002/(SICI)1521-3773(19990601)38:11<1652::AID-ANIE1652>3.0.CO;2-K

Reference yield:

: 160238-46-0
(2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal

: 243468-87-3
(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Guidance literature:: Multi-step reaction with 4 steps

1.1: 77 percent / 4 Angstroem sieves / toluene / -78 °C

2.1: 2,6-lutidine

3.1: catecholborane; (Ph₃P)3RhCl

3.2: 86 percent / H₂O₂; NaOH

4.1: (COCl)2; DMSO; Et₃N / -78 °C

With 2,6-dimethylpyridine; Wilkinson's catalyst; oxalyl dichloride; 4 A molecular sieve; dimethyl sulfoxide; triethylamine; benzo[1,3,2]dioxaborole; In toluene; 4.1: Moffatt-Swern oxidation;
DOI:10.1021/ja017885e

Reference yield:

: 243468-86-2
tert-Butyl-{(1S,2S)-1-[(R)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-but-3-enyloxy}-dimethyl-silane

: 243468-87-3
(3S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-3,5-dimethyl-hexanal

Guidance literature:: Multi-step reaction with 2 steps

1.1: catecholborane; (Ph₃P)3RhCl

1.2: 86 percent / H₂O₂; NaOH

2.1: (COCl)2; DMSO; Et₃N / -78 °C

With Wilkinson's catalyst; oxalyl dichloride; dimethyl sulfoxide; triethylamine; benzo[1,3,2]dioxaborole; 2.1: Moffatt-Swern oxidation;
DOI:10.1021/ja017885e