2,5-Dichloro-3,6-diethylpyrazine

Base Information

• Chemical Name: 2,5-Dichloro-3,6-diethylpyrazine
• CAS No.: 72875-84-4
• Molecular Formula: C8H10 Cl2 N2
• Molecular Weight: 205.0844
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60502136
• Nikkaji Number: J314.726F
• Wikidata: Q82354942
• Mol file: 72875-84-4.mol

Synonyms:2,5-Dichloro-3,6-diethylpyrazine;72875-84-4;2,5-Dichloro-3,6-diethyl-pyrazine;SCHEMBL6345951;DTXSID60502136;ZJCPOWPCEMWZHJ-UHFFFAOYSA-N;AKOS015962697;AC-17525;2,5-Dichloro-3,6-diethylpyrazine, AldrichCPR

Chemical Property of 2,5-Dichloro-3,6-diethylpyrazine

Chemical Property:

• Vapor Pressure: 0.077mmHg at 25°C
• Refractive Index: 1.533
• Boiling Point: 235.397°C at 760 mmHg
• Flash Point: 118.837°C
• PSA: 25.78000
• Density: 1.24g/cm³
• LogP: 2.90820
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 204.0221037
• Heavy Atom Count: 12
• Complexity: 127

Purity/Quality:

99% ^*data from raw suppliers

2,5-DICHLORO-3,6-DIETHYL-PYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(N=C(C(=N1)Cl)CC)Cl

Technology Process of 2,5-Dichloro-3,6-diethylpyrazine

There total 2 articles about 2,5-Dichloro-3,6-diethylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,6-diethyl-piperazine-2,5-dione (5625-42-3) → 2,5-dichloro-3,6-diethylpyrazine 4-oxide (72875-84-4)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate; In hexane; ethyl acetate;

Reference yield:

→ 2,5-dichloro-3,6-diethylpyrazine 4-oxide (72875-84-4)

Guidance literature:

α-Aminobuttersaeure-anhydrid-Va, PCl5/POCl3;

Reference yield: 93.0%

trimethylaluminum (75-24-1) + 2,5-dichloro-3,6-diethylpyrazine 4-oxide (72875-84-4) → 2,5-Diethyl-3,6-dimethylpyrazine (18903-30-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; hexane; for 4h; Heating;

upstream raw materials:

3,6-diethyl-piperazine-2,5-dione

Downstream raw materials:

C₃₈H₃₄N₄

2,5-Diethyl-3,6-bis-phenylethynyl-pyrazine

(E)-3,6-diethyl-2,5-distyrylpyrazine

Triethylpyrazin