4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Base Information

Chemical Name:4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride
CAS No.:1609075-17-3
Molecular Formula:C₂₉H₃₀BrN₃O₅*ClH
Molecular Weight:616.939
Hs Code.:

4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Synonyms:4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Suppliers and Price of 4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

There total 3 articles about 4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1609075-30-0
N-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N-{[1-(2-{[(4S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indol izino[1,2-b]quinolin-4-yl]oxy}-2-oxoethyl)cyclohexyl]methyl}-N⁵-carbamoyl-L-ornithinamide

: 1609075-17-3
4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: diethylenetriaminopentaacetic acid; sodium chloride / aq. buffer / 1 h / 21 °C

2: cathepsin B / aq. buffer / 20 - 40 °C

With diethylenetriaminopentaacetic acid; sodium chloride; cathepsin B; In aq. buffer;

Reference yield:

: 1609075-27-5
L-valyl-N-{[1-(2-{[(4S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4’:6,7]indolizino[1,2-b]quinolin-4-yl]oxy}-2-oxoethyl)cyclohexyl]methyl}-N⁵-carbamoyl-L-ornithinamide

: 1609075-17-3
4(S)-10-bromo-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl [1-(aminomethyl)cyclohexyl]acetate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: dicyclohexyl-carbodiimide; benzotriazol-1-ol / tetrahydrofuran / 3 h / 20 °C

1.2: 0.33 h / 20 °C

2.1: diethylenetriaminopentaacetic acid; sodium chloride / aq. buffer / 1 h / 21 °C

3.1: cathepsin B / aq. buffer / 20 - 40 °C

With diethylenetriaminopentaacetic acid; benzotriazol-1-ol; dicyclohexyl-carbodiimide; sodium chloride; cathepsin B; In tetrahydrofuran;