2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester

Base Information

• Chemical Name: 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester
• CAS No.: 88065-37-6
• Molecular Formula: C₂₉H₂₆N₂O₄S
• Molecular Weight: 498.602

Synonyms:2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester

Chemical Property of 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester

There total 2 articles about 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(2S,4S,6R,7R)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-tricyclo[4.2.0.02,4]octane-2-carboxylic acid (55658-34-9) + diazodiphenylmethane (908093-98-1) → 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.02.4>octane-2-carboxylic acid diphenylmethyl ester (88065-37-6)

Guidance literature:

In dichloromethane; for 1h;

DOI:10.1016/S0040-4020(01)92137-4

Reference yield:

benzophenone hydrazone (5350-57-2) → 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.02.4>octane-2-carboxylic acid diphenylmethyl ester (88065-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: MnO₂ / CH₂Cl₂ / 6.5 h

2: 85 percent / CH₂Cl₂ / 1 h

With manganese(IV) oxide; In dichloromethane;

DOI:10.1016/S0040-4020(01)92137-4

Reference yield: 82.0%

2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.02.4>octane-2-carboxylic acid diphenylmethyl ester (88065-37-6) → 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-(phenylacetyl)nitrosamino-5-thia-1-azatricyclo<4.2.0.02.4>-octane-2-carboxylic acid diphenylmethyl ester (88065-38-7)

Guidance literature:

With dinitrogen tetraoxide; In dichloromethane; below 0 degC;

DOI:10.1016/S0040-4020(01)92137-4

upstream raw materials:

(2S,4S,6R,7R)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-aza-tricyclo[4.2.0.0^2,4]octane-2-carboxylic acid

diazodiphenylmethane

benzophenone hydrazone

Downstream raw materials:

2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-(phenylacetyl)nitrosamino-5-thia-1-azatricyclo<4.2.0.0^2.4>-octane-2-carboxylic acid diphenylmethyl ester

2S-(2α,4α,6α,7α)-7-Chloro-4-methyl-8-oxo-5-thia-1-azatricyclo<4.2.0.0^2.4>-octane-2-carboxylic acid diphenylmethyl ester

2S-(2α,4α,6α)-7,7-Dibromo-4-methyl-8-oxo-5-thia-1-azatricyclo<4.2.0.0^2.4>-octane-2-carboxylic acid diphenylmethyl ester

2S-(2α,4α,6α,7α)-7-Chloro-4-methyl-8-oxo-5-thia-1-azatricyclo<4.2.0.0^2.4>-octane-2-carboxylic acid diphenylmethyl ester 5,5-dioxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 88065-37-6 2S-(2α,4α,6α,7β)-4-Methyl-8-oxo-7-phenylacetylamino-5-thia-1-azatricyclo-<4.2.0.0^2.4>octane-2-carboxylic acid diphenylmethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send