3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)

Base Information

Chemical Name:3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)
CAS No.:767272-87-7
Molecular Formula:C₁₁H₂₃NO₃
Molecular Weight:217.309
Hs Code.:
Mol file:767272-87-7.mol

Synonyms:3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)

Suppliers and Price of 3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)

Chemical Property:

PSA：72.72000
LogP:0.34010

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI)

There total 3 articles about 3,4-Pyrrolidinediol, 2-[(1R)-1-hydroxyheptyl]-, (2S,3S,4R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 228098-76-8
(2S,3S,4R)-2-<(1R)-1-Hydroxyheptyl>-1-<(1R)-2-hydroxy-1-phenylethyl>-3,4-dihydroxypyrrolidine

: 767272-87-7
(2S,3S,4R)-2-<(1R)-1-Hydroxyheptyl>pyrrolidine-3,4-diol

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; for 3h; Yield given;
DOI:10.1055/s-1999-3434

Reference yield:

: (2R)-2-<(2RS)-2,5-Dihydro-2-<(1RS)-1-hydroxyheptyl>-5-oxopyrrol-1-yl>-2-phenylethylbenzoate

: 767272-87-7
(2S,3S,4R)-2-<(1R)-1-Hydroxyheptyl>pyrrolidine-3,4-diol

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / OsO₄, N-methylmorpholine oxide hydrate, H₂O / acetone; 2-methyl-propan-2-ol / 48 h / Ambient temperature

2: 81 percent / LiAlH₄ / tetrahydrofuran / 12 h / Ambient temperature

3: H₂ / Pd(OH)2/C / methanol / 3 h

With osmium(VIII) oxide; lithium aluminium tetrahydride; water; hydrogen; 4-methylmorpholine N-oxide; palladium dihydroxide; In tetrahydrofuran; methanol; acetone; tert-butyl alcohol;
DOI:10.1055/s-1999-3434

Reference yield:

: 228098-70-2
(2R)-2-<(3S,4S)-3,4-Dihydroxy-(2S)-2-<(1R)-1-hydroxyheptyl>-5-oxopyrrolidin-1-yl>-2-phenylethylbenzoate

: 767272-87-7
(2S,3S,4R)-2-<(1R)-1-Hydroxyheptyl>pyrrolidine-3,4-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / LiAlH₄ / tetrahydrofuran / 12 h / Ambient temperature

2: H₂ / Pd(OH)2/C / methanol / 3 h

With lithium aluminium tetrahydride; hydrogen; palladium dihydroxide; In tetrahydrofuran; methanol;
DOI:10.1055/s-1999-3434