[dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane

Base Information

• Chemical Name: [dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane
• CAS No.: 947770-24-3
• Molecular Formula: C₂₀H₃₃NSi₃
• Molecular Weight: 371.745
• Mol file: 947770-24-3.mol

Synonyms:[dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane

Chemical Property of [dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane

Chemical Property:

Purity/Quality:

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Technology Process of [dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane

There total 1 articles about [dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

2-bromo-6-phenylpyridine (39774-26-0) + bromodimethylsilylbis(trimethylsilyl)methane (86932-21-0) → [dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane (947770-24-3)

Guidance literature:

2-bromo-6-phenylpyridine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.333333h;

bromodimethylsilylbis(trimethylsilyl)methane; In diethyl ether; hexane; Further stages.;

DOI:10.1139/V07-063

Reference yield: 76.0%

[dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methane (947770-24-3) + methyllithium (917-54-4) + dimethylaluminum chloride (1184-58-3) → ([dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methyl)dimethylaluminum (947770-21-0)

Guidance literature:

In hexane; byproducts: CH4, LiCl; Schlenk technique; LiCH3 in THF/cumene added dropwise to pyridyl-compd. in THF at room temp., stirred for 1 h, evapd. under vac., residue dissolved in hexane, Me2AlCl in hexane slowly added at 0°C, stirred at room temp. for 16 h; evapn. under vac., solid extd. with ether, combined extracts evapd., residue sublimed at 140°C and 10**-3 mbar, crystn. from ether at -30°C; elem. anal.;

DOI:10.1139/V07-063

upstream raw materials:

2-bromo-6-phenylpyridine

bromodimethylsilylbis(trimethylsilyl)methane

Downstream raw materials:

([dimethyl(6-phenylpyrid-2-yl)silyl]bis(trimethylsilyl)methyl)dimethylaluminum

Refernces