(2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine

Base Information

• Chemical Name: (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine
• CAS No.: 77857-65-9
• Molecular Formula: C₂₂H₃₅NO
• Molecular Weight: 329.526
• Mol file: 77857-65-9.mol

Synonyms:(2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine

Chemical Property of (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine

There total 1 articles about (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-benzyl-2-methoxyethylamine (64715-80-6) + cyclododecanone (830-13-7) → (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine (77857-65-9)

Guidance literature:

With trifluoroacetic acid; In toluene; for 35h; Heating;

DOI:10.1021/ja00401a029

Reference yield:

1-Iodohexane (638-45-9) + (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine (77857-65-9) → (R)-(+)-2-n-hexylcyclododecanone (77857-96-6) + cyclododecanone (830-13-7)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -40 deg C -> room temperature; 65 deg C, 1 h, 2.) 65 deg C, 1 h;

DOI:10.1021/ja00401a029

Reference yield:

1-Iodohexane (638-45-9) + (2S)-(-)-(N-cyclododecylidine)-1-methoxy-3-phenyl-2-propylamine (77857-65-9) → (R)-13-Hexyl-oxacyclotridecan-2-one (65883-63-8) + cyclododecanone (830-13-7)

Guidance literature:

With peracetic acid; diethyl ether; boron trifluoride; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1021/ja00401a029

upstream raw materials:

(S)-1-benzyl-2-methoxyethylamine

cyclododecanone

Downstream raw materials:

cyclododecanone

(R)-2-(2-methoxyethyl)cyclododecanone

(S)-(+)-2-(2-methoxyethyl)cyclododecanone

(R)-(+)-2-n-hexylcyclododecanone

Refernces