(S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

Base Information

Chemical Name:(S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS No.:1238365-76-8
Molecular Formula:C₃₁H₂₈N₂O₃
Molecular Weight:476.575
Hs Code.:

Synonyms:(S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Chemical Property of (S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Technology Process of (S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

There total 1 articles about (S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 79261-58-8
(S)-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylic acid 2-benzyl ester

: 91-00-9
Benzhydrylamine

: 1238365-76-8
(S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;
DOI:10.1016/j.tetasy.2010.04.017

Reference yield: 80.0%

: 1238365-76-8
(S)-benzyl 3-(benzhydrylcarbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

: 1238365-83-7
(S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid benzhydryl-amide

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; for 2h; under 760.051 Torr;
DOI:10.1016/j.tetasy.2010.04.017