Technology Process of 4-(2-methoxy-5-methylphenyl)pentanal
There total 8 articles about 4-(2-methoxy-5-methylphenyl)pentanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
hexane; toluene;
at -70 ℃;
for 4h;
DOI:10.1002/jccs.200100128
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 70 percent / 80 percent phosphoric acid / toluene / 18 h / 20 °C
2.1: 92.6 percent / K2CO3 / acetone / 36 h / Heating
3.1: O3; sodium bicarbonate / CH2Cl2 / -78 - 0 °C
3.2: 50 percent / Et3N; Ac2O / CH2Cl2 / 4 h / 20 °C
4.1: 99 percent / BF3*Et2O / 15 h / 20 °C
5.1: 90 percent / Raney nickel / ethanol / 17 h / Heating
6.1: 91.7 percent / DIBAL-H / toluene; hexane / 4 h / -70 °C
With
phosphoric acid; boron trifluoride diethyl etherate; nickel; diisobutylaluminium hydride; sodium hydrogencarbonate; potassium carbonate; ozone;
In
ethanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1002/jccs.200100128
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 92.6 percent / K2CO3 / acetone / 36 h / Heating
2.1: O3; sodium bicarbonate / CH2Cl2 / -78 - 0 °C
2.2: 50 percent / Et3N; Ac2O / CH2Cl2 / 4 h / 20 °C
3.1: 99 percent / BF3*Et2O / 15 h / 20 °C
4.1: 90 percent / Raney nickel / ethanol / 17 h / Heating
5.1: 91.7 percent / DIBAL-H / toluene; hexane / 4 h / -70 °C
With
boron trifluoride diethyl etherate; nickel; diisobutylaluminium hydride; sodium hydrogencarbonate; potassium carbonate; ozone;
In
ethanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1002/jccs.200100128
