2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol

Base Information

• Chemical Name: 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol
• CAS No.: 864373-00-2
• Molecular Formula: C₃₄H₃₇O₁₂P
• Molecular Weight: 668.634

Synonyms:2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol

Chemical Property of 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol

There total 6 articles about 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5,6-tri-O-acetyl-1,4-di-O-benzyl-D-myo-inositol (864373-08-0) + N,N-diethyl-1,5-dihydro-3H-2,4,3-benzodioxaphosphepin-3-amine (82372-35-8) → 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ5-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol (864373-00-2)

Guidance literature:

2,5,6-tri-O-acetyl-1,4-di-O-benzyl-D-myo-inositol; N,N-diethyl-1,5-dihydro-3H-2,4,3-benzodioxaphosphepin-3-amine; With 1H-tetrazole; In dichloromethane; at 20 ℃; for 12h;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -40 - 20 ℃;

DOI:10.1002/ejoc.200400911

Reference yield:

(1R,2S,3S,4R)-2,3-di-O-acetyl-1,4-di-O-benzylconduritol B (864372-75-8) → 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ5-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol (864373-00-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaIO₄; RuCl₃*3H₂O / acetonitrile; H₂O / 0.17 h / cooling

2.1: p-TSA*H₂O / tetrahydrofuran / 24 h

2.2: AcOH; water / 1 h / 20 °C

3.1: 1H-tetrazole / CH₂Cl₂ / 12 h / 20 °C

3.2: m-CPBA / CH₂Cl₂ / -40 - 20 °C

With 1H-tetrazole; ruthenium trichloride; sodium periodate; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; water; acetonitrile;

DOI:10.1002/ejoc.200400911

Reference yield:

5,6-di-O-acetyl-1,4-di-O-benzyl-D-myo-inositol (864372-97-4) → 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ5-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol (864373-00-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: p-TSA*H₂O / tetrahydrofuran / 24 h

1.2: AcOH; water / 1 h / 20 °C

2.1: 1H-tetrazole / CH₂Cl₂ / 12 h / 20 °C

2.2: m-CPBA / CH₂Cl₂ / -40 - 20 °C

With 1H-tetrazole; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1002/ejoc.200400911

upstream raw materials:

2,5,6-tri-O-acetyl-1,4-di-O-benzyl-D-myo-inositol

N,N-diethyl-1,5-dihydro-3H-2,4,3-benzodioxaphosphepin-3-amine

(1R,2S,3S,4R)-2,3-di-O-acetyl-1,4-di-O-benzylconduritol B

5,6-di-O-acetyl-1,4-di-O-benzyl-D-myo-inositol

Downstream raw materials:

D-myo-inositol-3-phosphate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 864373-00-2 2,5,6-tri-O-acetyl-1,4-di-O-benzyl-3-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol

Send

Send

Metric Ton KG G Pound L ML

Send

Send