Technology Process of C24H29NO4
There total 6 articles about C24H29NO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
acetonitrile;
at 20 ℃;
for 1h;
optical yield given as %de;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/ol201704g
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrahydrofuran; toluene / 3.5 h / -78 °C / Inert atmosphere
2: hydrogenchloride; water / methanol / 2 h
3: potassium carbonate / water; acetone; toluene / 1 h / 20 °C
4: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / 20 °C / Inert atmosphere
5: boron trifluoride diethyl etherate / acetonitrile / 1 h / 20 °C / Inert atmosphere
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; boron trifluoride diethyl etherate; water; potassium carbonate;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene; acetonitrile;
1: Grignard addition / 5: Michael addition;
DOI:10.1021/ol201704g
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrahydrofuran; toluene / 3.5 h / -78 °C / Inert atmosphere
2: hydrogenchloride; water / methanol / 2 h
3: potassium carbonate / water; acetone; toluene / 1 h / 20 °C
4: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / 20 °C / Inert atmosphere
5: boron trifluoride diethyl etherate / acetonitrile / 1 h / 20 °C / Inert atmosphere
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; boron trifluoride diethyl etherate; water; potassium carbonate;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene; acetonitrile;
1: Grignard addition / 5: Michael addition;
DOI:10.1021/ol201704g
