C₁₄H₁₆F₃NO₄

Base Information

Chemical Name:C₁₄H₁₆F₃NO₄
CAS No.:1458674-46-8
Molecular Formula:C₁₄H₁₆F₃NO₄
Molecular Weight:319.281
Hs Code.:

C<sub>14</sub>H<sub>16</sub>F<sub>3</sub>NO<sub>4</sub>

Synonyms:C₁₄H₁₆F₃NO₄

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₄H₁₆F₃NO₄

Chemical Property:

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Technology Process of C₁₄H₁₆F₃NO₄

There total 1 articles about C₁₄H₁₆F₃NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: ethyl (S)-4,4,4-trifluoro-3-aminobutyrate hydrochloride

: 501-53-1,94274-21-2
benzyl chloroformate

: 1458674-46-8
C₁₄H₁₆F₃NO₄

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.tet.2013.08.051

Reference yield: 91.0%

: 1458674-46-8
C₁₄H₁₆F₃NO₄

: 1458674-47-9
C₁₂H₁₂F₃NO₄

Guidance literature:: With lithium hydroxide monohydrate; water; In 1,4-dioxane; at 0 - 20 ℃;
DOI:10.1016/j.tet.2013.08.051

Reference yield:

: 1458674-46-8
C₁₄H₁₆F₃NO₄

: 1458674-49-1
C₁₆H₂₀F₃NO₄

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide monohydrate; water / 1,4-dioxane / 0 - 20 °C

2: sulfuric acid / dichloromethane / 0 - 20 °C

With lithium hydroxide monohydrate; sulfuric acid; water; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.tet.2013.08.051