2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole

Base Information

• Chemical Name: 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole
• CAS No.: 182678-82-6
• Molecular Formula: C₁₂H₁₆N₂O₂S
• Molecular Weight: 252.337
• Mol file: 182678-82-6.mol

Synonyms:2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole

Chemical Property of 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole

There total 1 articles about 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl-2,3-diaza-4-methyl-4-acetoxypent-2-enoate (21732-11-6) + phenylmethanethiol (100-53-8) → 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole (182678-82-6)

Guidance literature:

With lead(IV) acetate; potassium hydroxide; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1.) CH₂Cl₂, AcOH, 2.) CH₂Cl₂, reflux, 3.) CH₂Cl₂, 2 h;

DOI:10.1139/v96-165

Reference yield: 75.0%

dichloromaleic acid anhydride (1122-17-4) + 2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole (182678-82-6) → 6-Benzylsulfanyl-3,4-dichloro-6-methoxy-pyran-2,5-dione

Guidance literature:

In benzene; at 80 ℃; sealed;

DOI:10.1139/v96-165

Reference yield: 32.0%

2-Benzylsulfanyl-2-methoxy-5,5-dimethyl-2,5-dihydro-[1,3,4]oxadiazole (182678-82-6) → Z-1,2-bis(benzylthio)-1,2-dimethoxyethene + E-1,2-bis(benzylthio)-1,2-dimethoxyethene

Guidance literature:

In benzene; Heating;

DOI:10.1139/v96-165

upstream raw materials:

methyl-2,3-diaza-4-methyl-4-acetoxypent-2-enoate

phenylmethanethiol